The Ghibli’s standard lane departure warning system alerts a temporarily inattentive driver when the vehicle begins to leave its lane and gently nudges the vehicle back towards its lane. A lane departure warning system costs extra on the E-Class Sedan.
To help make backing out of a parking space safer, the Ghibli has standard Rear Cross Path, helping the driver avoid collisions. Mercedes charges extra for Rear Cross-Traffic Alert on the E-Class Sedan.
Both the Ghibli and the E-Class Sedan have standard driver and passenger frontal airbags, front side-impact airbags, driver knee airbags, side-impact head airbags, front seatbelt pretensioners, height adjustable front shoulder belts, four-wheel antilock brakes, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, daytime running lights, blind spot warning systems and rearview cameras.

