Both the Ghost and LS have child safety locks to prevent children from opening the rear doors. The Ghost has power child safety locks, allowing the driver to activate and deactivate them from the driver's seat and to know when they're engaged. The LS’ child locks have to be individually engaged at each rear door with a manual switch. The driver can’t know the status of the locks without opening the doors and checking them.
The Ghost has standard Active Head Restraints, which use a specially designed headrest to protect the driver and front passenger from whiplash. During a rear-end collision, the Active Head Restraints system moves the headrests forward to prevent neck and spine injuries. At the same time the pretensioning seatbelts fire, removing slack from the belts. The LS doesn’t offer a whiplash protection system.
An active infrared night vision system standard on the Ghost helps the driver to more easily detect people, animals or other objects in front of the vehicle at night. Using an infrared camera and near-infrared lights to detect heat, the system then projects the image on the windshield, near the driver’s line of sight. The LS doesn’t offer a night vision system.
Both the Ghost and the LS have standard driver and passenger frontal airbags, front side-impact airbags, driver and front passenger knee airbags, side-impact head airbags, front and rear seatbelt pretensioners, four-wheel antilock brakes, all wheel drive, traction control, electronic stability systems to prevent skidding, crash mitigating brakes, post-collision automatic braking systems, daytime running lights, lane departure warning systems, blind spot warning systems, around view monitors, rear cross-path warning and driver alert monitors.
The Rolls-Royce Ghost weighs 540 to 651 pounds more than the Lexus LS. The NHTSA advises that heavier cars are much safer in collisions than their significantly lighter counterparts.

